About Uses Of Naltrexone
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Top Questions and Answers
Naltrexone? I know Naltrexone can be used to block the effects of alcahol "BUT" can it also be used to prevent a hangover if taken just before you collaps (pass out) after a night out on the bottle......

bigramdaddy replied: "i believe naltrexone is only beneficial for cravings, it's supposed to reduce your cravings to want to drink. it's a pill designed to help alcoholics, i don't think it's capable of anything you mentioned."

Has anyone used Low Dose Naltrexone for Crohns or Multiple Sclerosis? I know people have used it, but I am looking for personal experiences with it.

pelops_dl replied: "A google search will profide a number of anecdotes, but those really won't give you a good idea of what you need to know. Your best bet is to talk to your doctor and ask him/her about the side effects, and efficacy. What does the scientific literature (journal articles) say as a whole? This is something your doctor may even have to research to find out for you. That's far more useful than asking for anecdotes. It is also the best way to arrive at an answer that is in line with the facts."

pcheesewhiz replied: "Your doctor will probably be useless in helping you get any kind of handle on the facts about Low Dose Naltrexone. There is money to be made when doctors prescribe medicines for which the patents have not expired. This is not the case with Naltrexone which has been on the market for almost a quarter of a century. Since your doctor gets his or her info on drugs from the drug reps, they will not be educated about Naltrexone. I have been taking Low Dose Naltrexone for multiple sclerosis for three and a half years now and it has given me my life back. Prior to taking it, I was on Copaxone and spent the day going from the bed to the sofa and then back again. In short my life was a living hell. Once I started taking Low Dose Naltrexone, I went back to work and the gym and began to have a social life again. Not everyone who has MS experiences as good a result from Copaxone as I did, but many do in fact have a very positive experience with it. You need to be on the correct dosage of 4.5 milligrams (unless you have spasicitity in which case you need to stay at 3.0 milligrams) and stay on it for at least three months to get the maximum benefit. I do not know the correct dosage for Crohns or any of the other autoimmune diseases-just the correct amount for MS. Keep in mind that that LDN cannot reverse the damage to the myelin. So the LDN will have no effect on any symptom that is the consequence of myelin damage. Your doctor gets no training in parmaceuticals in medical school. IT is just not part of the curriculum. Drug reps are the ones who educate the doctors on what to give thier patients. Drug reps are rewarded on the basis of promoting the drugs that have the highest profits. These are the drugs that are the newest that still have a patent. Drug companies openly discouage their reps from recommending anything other than drugs upon which they have a patent. They do this by giving bonuses and the highest salaries to the reps who do the best job at promoting the high dollar drugs. Conversely, reps who don't do this are either getting horrendous evaluations or they are already fired. Doctors are also given bonuses by the pharmaceutical companies on the basis of the drugs they prescribe. As a consequence of the aforementioned, may I suggest that you do your own research. Simply go to LDN.ORG and you will find many, many web sites that have infor on the drug and the various auto-immune diseases for which it is effective. Keep in mind that all the current research indicates that more research needs to be done. This is because giving any drug the total green light always means that they will not get another contract to do research on that drug. In other words approving a drug would only put them out of another job. Keep in mind also that drugs usually get approved because the drug company is trying to get apporval for them so that they can get a patent. But since Naltrexone was approved for the treatment of drug and alcohol abuse years and years ago, the patent has expired and therefore the drug companies cannot make big money on it. Since they cannot make the big money now on it, they will not put one penny into doing any research to get it approved for another use although it has the possibility to improve the lives of hundreds of thousends of people. They are in this for profit and could not care less about humanitarian purposes. Sad, isn't it?"

Naltrexone used for Sexual Addiction? My doctor just prescribed Naltrexone for me in attempt to treat my sexual addiction problem. Does anyone know about how successful this medication works for the treatment of sexual addictions? The drug is really used for Alcohol abuse treatment and people addicted to Heroion. I checked the net but could not find anything that mentioned specifically of its use to treat sexual addictions. I am a male, by the way. Also I am worried can it make a man have erectile dysfunction?

NORUN replied: "http://www.opioids.com/naltrexone/antisexual.html this might help you. but it looks to be true!"

Elusive replied: "I wouldn't personally mess with any sex addiction drugs. Just conquer it yourself - you don't know what will happen."

Alcoholics. Have any of you had any luck with the drug Naltrexone? I have seen very conflicing reports. AA will not condone it due to their "no chemical solution" policy, yet I have seen studies that show it significantly reduces cravings. I am also interested in the "Sinclair Method" in which Naltrexone is used to block the the brain's endorphine reward for drinking. Any practical info will be appreciated.

EmilyRose replied: "The controversy is over the morality, not the efficacy. There's little debate that Naltrexone helps people deal with alcohol addiction. AA doesn't support it because it goes against their philosophy, not because it doesn't work. We talked about it in my psychobiology class last semester as an effective medication to aid in recovery from alcoholism. My professor said it's effective, and considering that her primary research interest is alcohol addiction, I think she'd know. Naltrexone is an opiate receptor antagoist, which, as you said, basically reduces the activation of the reward pathways during drinking. Basically, it makes it so that having one drink, or even several drinks, is less likely to result in a relapse because it produces a less strong reward. As I said, it's efficacy in reducing relpse in recovering alcoholics has been well established in clinical trials."

Naltrexone v.s Heroin & Alcohol? I heard that if you are taking Naltrexone and try a Heroin there will be no efects, or maybe u will feel sick?Which one is true?Is there anyway you can feel high from Heroin while using Naltrexone?How can u get an overdose from Heroin while using Naltrexone ?What about Naltrexone v.s Alcohol?WIll you feel someting if u drink while taking Naltrexone oraly? Thanx

Simonizer1218 replied: "Wow, that was a lot. First, naltrexone is an opiate antagonist, meaning it blocks some of the receptors that opiates usually occupy. So, given an appropriate dose, it should block the effect of heroin. If one gets sick, it will be because of withdrawal. Since alcohol intoxication involves the opiate system in the brain, as well as many other transmitter systems, naltrexone has received some attention in this arena also, and has been used to treat alcoholism. Yes, you can still get drunk on alcohol while taking naltrexone, but the naltrexone is supposed to reduce the urge to drink."

Michael S replied: "Naltrexone is a MU antagonist meaning that it will go onto the MU receptors (the main receptors that heroin and all opioids hit and activate) so if someone was on naltrexone and had enough of it taking a dose of heroin depending on the amont of heroin they wouldn't get as many effects. Now heroin and other opioids do hit other opioid receptors such as kappa and delta (i think thats what its called) these effects aren't as well known but they are thought to not be positive. the high/pain relief is thought to be primarily from the MU receptors. Since naltrexone blocks primarily the mu receptors those other receptors would be hit and some effects would be seen. Alcoholics are sometimes given naltrexone for no other reason then it helps calm them down and has been shown to help prevent relapses. There really is no pharmacological reason to give naltrexone to alcoholics. If you took naltrexone while drinking it would NOT alter the effects of alcohol. Naltrexone is a competitive inhibitor for the MU receptors so it still is possible to OD while on naltrexone. Number 1 naltrexone won't last forever in the body it will be gone after i'd say 8 hours. Number 2 naltrexone althought it can bind to the MU receptor it acts competitively which means if morphine or heroin were at much higher concentraions it could displace the naltrexone and give the MU effects. By the way the ODing part is also from the MU effects. So yes you can die from heroin even if on naltrexone. Of course all the other complications from heroin high risk for infection due to the IV use, heart infections, and addiction still exist. You'd have to be pretty stupid to use that stuff anyway but people do everyday."

Low Dose Naltrexone and MS? Is using Naltrexone a good remedy for treating MS?

Chelsea replied: "Yes, many have been taking it for years, especially with MS. LDN stimulates endorphins and met-enkephalin (opioid growth factor) which serve to re balance the immune system so it behaves correctly, and thus stops attacking the host. The beta endorphins and met-enkephalin also stimulate the proliferation of repair cells in the body. They also act to counteract the effects of oxidative stress which has been linked with the degenerative progressive stage of MS, and may well prove to be a primary process in MS. Essentially, the combination of a correctly functioning immune system and the proliferation of repair cells, like the oligodendrocytes that make myelin for the nerves, and the antioxidant effects work to overcome and even reverse the effects of MS . Permanent damage however will have to wait for stem cell therapy, but this explains some of the miraculous improvements that have been recorded with LDN. As we all know, autoimmune diseases are a result of an under-active immune system by showing low beta-endorphin levels. Endorphins are what regulate the immune system. When you raise the endorphin level, disease progression starts to slow and can come to a complete halt in many. LDN raises endorphin levels."

Naltrexone v.s Heroin??? I heard that if you are taking Naltrexone and try a Heroin there will be no efects, or maybe u will feel sick?Which one is true?Is there anyway you can feel high from Heroin while using Naltrexone?How can u get an overdose from Heroin while using Naltrexone ?What about Naltrexone v.s Alcohol? Thanx

Phoenix replied: "Do not use narcotic drugs or alcohol while taking naltrexone oral. Never try to overcome the effects of the medication by taking large doses of narcotic drugs or alcohol. Doing so could result in dangerous effects, including coma and death. Ask your doctor before using any prescription or over-the-counter medicine to treat a cold, cough, diarrhea, or pain while taking naltrexone oral. These medicines may contain narcotics or alcohol. Naltrexone oral can cause side effects that may impair your thinking or reactions. Be careful if you drive or do anything that requires you to be awake and alert. Carry an ID card or wear a medical alert bracelet stating that you are using naltrexone, in case of emergency. Any doctor, dentist, or emergency medical care provider who treats you should know that you are using this medication"

ash v replied: "Naltrexone is an opioid receptor antagonist used primarily in the management of alcohol dependence and opioid dependence. The blockade of opioid receptors is the basis behind its action in the management of opioid dependence—it reversibly blocks or attenuates the effects of opioids. Naltrexone is sometimes used for rapid detoxification regimens for opioid dependence. The main use of naltrexone is for the treatment of alcohol dependence. It essentially counters the effect of opioids and alcohol."

naltrexone and perocet? hi, im in no way an opiate addict, but i recently took a percocet last night. i am using naltrexone for alcohol problems. i heard that your not supposed to combine the two in case of a withdrawel or something ? ?but im not an opiate addict, so i was wondering is it ok to take the first dose of naltrexone tonight if i took a percocet last night? i could swear i read somewhere your supposed to wait a few days or something..

Blondie replied: "you need to call a pharmacy instead of asking on here."

any experiences with naltrexone? did it work for you? how long where you on it? did your body and mind get used to it?

Avery Jane replied: "It's black-boxed for liver enzyme elevation. The IM drug can cause nasty injection-site reactions. Get your blood drawn when they tell you to."

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